Livre Detoxseafication – Bibliographie et Références

Parce que la thématique originale du livre « Detoxseafication » sur les bienfaits de l’eau de mer a de quoi surprendre certains confrères, voici une liste non exhaustive des sources ayant étayé mon propos. J’essaierai de tenir à jour cette biblio avec les publications les plus récentes.

Vous remarquerez que certains sujets comme l’impact psychologique de l’environnement marin, les indications ORL ou les propriétés de l’eau de mer des profondeurs ont largement été développés ces dernières années dans les quelques pays qui s’intéressent à ces recherches fondamentales.

Les références françaises manquent par défaut de recherches récentes et à cause de la disparition de certaines sources citées dans ce livre qui remontent avant les années 1970. L’un de mes objectifs est de relancer la recherche dans le domaine de la médecine marine et de la thalassothérapie médicale.

Je suis intéressé par toute publication originale sur les recherches ayant porté sur les propriétés médicinales de l’eau de mer. N’hésitez pas à me contacter pour me les transmettre.

Espaces Bleus & Impact Psychologique

Katherine Ashbullby, Mathew White, Sabine Pahl & Michael Depledge. The psychological benefits of visiting natural environments: Differential effects of coast, countryside & urban open space on positive affect. School of Psychology, University of Plymouth / European Centre for Environment & Human Health, Peninsula College of Medicine & Dentistry, Universities of Exeter & Plymouth.

Mathew White, Amanda Smith, Kelly Humphryes, Sabine Pahl, Deborah Snelling, Michael Depledge. Blue space: The importance of water for preference, affect, and restorativeness ratings of natural and built scenes. Journal of Environmental Psychology, 30, 482-493.

Tanja-Dijkstra, K., Pahl, S., White, M.P., Andrade, J., & Moles, D. (2013). Virtual nature and pain reduction. Article en préparation.

Nutsford D, Pearson AL, Kingham S, Reitsma F. Residential exposure to visible blue space (but not green space) associated with lower psychological distress in a capital city. Health Place. 2016 Mar 11;39:70-78. doi: 10.1016/j.healthplace.2016.03.002.

Ashbullby, K., Pahl, S., Webley, P., White, M., 2013. The beach as a setting for families’ health promotion: a qualitative study with parents and children living in coastal regions in Southwest England. Health Place. healthplace.2013.06.005.

Herzog, T.R., 1985. A cognitive analysis of preference for waterscapes. J. Environ. Psychol. 5, 225–241.

Karmanov, D., Hamel, R., 2008. Assessing the restorative potential of contemporary urban environment(s): beyond the nature versus urban dichotomy. Landsc. Urban Plan. 86, 115–125.

Kearns, R.A., Collins, D., Conradson, D., 2014. A healthy island blue space: from space of detention to site of sanctuary. Health Place 30, 107–115.

Völker, S., Kistemann, T., 2011. The impact of blue space on human health and wellbeing – Salutogenetic health effects of inland surface waters: a review. Int. J. Hyg. Environ. Health 214, 449–460. ijheh.2011.05.001.

Völker, S., Kistemann, T., 2013. “I’m always entirely happy when I’m here!” Urban blue enhancing human health and well-being in Cologne and Düsseldorf, Germany. Soc. Sci. Med. 78, 113–124. socscimed.2012.09.047.

Wheeler, B.W., White, M., Stahl-Timmins, W., Depledge, M., 2012. Does living by the coast improve health and wellbeing? Health Place 18, 1198–1201. http://dx.doi. org/10.1016/j.healthplace.2012.06.015.

White, M., Alcock, I., Wheeler, B.W., Depledge, M., 2013. Coastal proximity, health and well-being: results from a longitudinal panel survey. Health Place 23, 97–103.

White, M., Smith, A., Humphryes, K., Pahl, S., Snelling, D., Depledge, M., 2010. Blue space: the importance of water for preference, affect, and restorativeness ratings of natural and built scenes. J. Environ. Psychol. 30, 482–493. http://dx.doi. org/10.1016/j.jenvp.2010.04.004.

Atchley RA, Strayer DL, Atchley P (2012) Creativity in the Wild : Improving Creative Reasoning through Immersion in Natural Settings. PLoS ONE 7(12): e51474. doi:10.1371/journal.pone.0051474 /

Berman MG, Jonides J, Kaplan S (2008) The cognitive benefits of interacting with nature. Psychological Science 19(12): 1207. doi: 10.1111/j.1467-9280.2008.02225.x

Kaplan S (1995) The restorative benefits of nature: Toward an integrative framework. Journal of Environmental Psychology 15(3): 169–182. doi: 10.1016/0272-4944(95)90001-2

Hartig T, Mang M, Evans GW (1991) Restorative effects of natural environment experiences. Environment and Behavior 23(1): 3–26. doi: 10.1177/0013916591231001

Tennessen CM, Cimprich B (1995) Views to nature: Effects on attention. Journal of Environmental Psychology 15(1): 77–85. doi: 10.1016/0272-4944(95)90016-0

Eau de Mer & Voies Respiratoires

Garavello W. et al. Hypersaline nasal irrigation in children with symptomatic seasonal allergic rhinitis: a randomized study. Pediatr Allergy Immunol. 2003 Apr;14(2):140-3.

Garavello W et al. Nasal lavage in pregnant women with seasonal allergic rhinitis: a randomized study. Int Arch Allergy Immunol. 2010;151(2):137-41. doi: 10.1159/000236003. Epub 2009 Sep 15.

Li H. et al. Nasal saline irrigation facilitates control of allergic rhinitis by topical steroid in children. ORL J Otorhinolaryngol Relat Spec. 2009;71(1):50-5.

Šlapak I, Skoupá J, Strnad P, Horník P. Efficacy of isotonic nasal wash (seawater) in the treatment and prevention of rhinitis in children. Arch Otolaryngol Head Neck Surg 2008;134:67-74.

Tano  LTano  K A daily nasal spray with saline prevents symptoms of rhinitis.  Acta Otolaryngol 2004;124 (9) 1059- 1062

Harvey R. et al. Nasal saline irrigations for the symptoms of chronic rhinosinusitis. Cochrane Database Syst Rev. 2007 Jul 18;(3):CD006394.

Culig J. Efficiency of hypertonic and isotonic seawater solutions in chronic rhinosinusitis. Med Glas (Zenica). 2010 Aug;7(2):116-23.

Traissac L, Ohayon-Courtes C, Dufour P, Bordenave L. Nasal washing with Physiomer … 10 years later: 1988-1998. Rev Laryngol Otol Rhinol (Bord). 1999;120(2):133-5.

Süslü N et al. Effects of buffered 2.3%, buffered 0.9%, and non-buffered 0.9% irrigation solutions on nasal mucosa after septoplasty. Eur Arch Otorhinolaryngol. 2009 May;266(5):685-9.

Brown CL. Nasal irrigations: good or bad? Curr Opin Otolaryngol Head Neck Surg. 2004 Feb;12(1):9-13.

Mihoko I. et. al. The effectiveness of nasal irrigation in the treatment of infant nasal problems. Japanese Journal of Rhinology 38 (2):230-234, 1999.

Emer P. Reeves, Kevin Molloy, Kerstin Pohl, and Noel G. McElvaney. Hypertonic Saline in Treatment of Pulmonary Disease in Cystic Fibrosis. ScientificWorldJournal. 2012; 2012: 465230.

Eau de Mer des Profondeurs – Deep-Sea Water

Bak JP et al. Application of concentrated deep sea water inhibits the development of atopic dermatitis-like skin lesions in NC/Nga mice. BMC Complement Altern Med. 2012 Jul 26;12:108.

Nomura, I. 1995. Kaiyo shinsousui ni yoru atopy sei hihuen no tiryou. (Medical treatment of atopic dermatitis using deep seawater), Magazine Kaigan 34 (2): 7-10. [In Japanese]

Ming-Jyh Sheu et al. Deep Sea Water Modulates Blood Pressure and Exhibits Hypolipidemic Effects via the AMPK-ACC Pathway: An in Vivo Study. Mar Drugs. 2013 Jun; 11(6): 2183–2202.

Ha BG et al. Modulation of glucose metabolism by balanced deep-sea water ameliorates hyperglycemia and pancreatic function in streptozotocin-induced diabetic mice. PLoS One. 2014 Jul 11;9(7):e102095.

Yoshioka S. et al. Pharmacological activity of deep-sea water: examination of hyperlipemia prevention and medical treatment effect. Biol Pharm Bull. 2003 Nov;26(11):1552-9.

Fu ZY. Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects. J Med Food. 2012 Jun;15(6):535-41. doi: 10.1089/jmf.2011.2007. Epub 2012 Mar 16.

Miyamura M. Difference between deep seawater and surface seawater in the preventive effect of atherosclerosis. Biol Pharm Bull. 2004 Nov;27(11):1784-7.

Radhakrishnan G. Intake of dissolved organic matter from deep seawater inhibits atherosclerosis progression. Biochem Biophys Res Commun. 2009 Sep 11;387(1):25-30. Epub 2009 Jun 18.

Hataguchi Y, Tai H, Nakajima H, Kimata H (2005) Drinking deep-sea water restores mineral imbalance in atopic eczema/dermatitis syndrome. Eur J Clin Nutr 59: 1093–1096

Kimata H, Tai H, Nakagawa K, Yokoyama Y, Nakajima H, et al. (2002) Improvement of skin symptoms and mineral imbalance by drinking deep sea water in patients with atopic eczema/dermatitis syndrome (AEDS). Acta Medica (Hradec Kralove). 45: 83–84

Kawahara K, Tancharoen S, Hashiguchi T, Unoshima M, Ito T, et al. (2007) Inhibition of HMGB1 by deep ocean water attenuates endotoxin-induced sepsis. Med Hypotheses 68: 1429–1430

Chen IS, Chang YY, Hsu CL, Lin HW, Chang MH, et al. (2013) Alleviative effects of deep-seawater drinking water on hepatic lipid accumulation and oxidation induced by a high-fat diet. J Chin Med Assoc76: 95–101

Nicholas Szary. High Intrinsic Aerobic Capacity Protects against Ethanol-Induced Hepatic Injury and Metabolic Dysfunction: Study Using High Capacity Runner Rat Model. Biomolecules 2015, 5(4), 3295-3308.

Kawada M, Takeuchi H, Con SA, Yamamoto E, Yasukawa T, et al. (2012) Antibacterial Activities of Refined Deep Seawater on Helicobacter pylori. J Medical Microbiol Diagnosis S1: 002

Kang SM et al. Effect of yogurt containing deep sea water on health-related serum parameters and intestinal microbiota in mice. J Dairy Sci. 2015 Sep;98(9):5967-73. doi: 10.3168/jds.2015-9492. Epub 2015 Jul 2.

Kyu-Shik Lee et al. Suppression of cancer progression and metastasis in HT-29 human colorectal adenocarcinomas by deep sea water. Biotechnology and Bioprocess Engineering. February 2013, Volume 18, Issue 1, pp 194–200

Kim S, et al. Mineral-enriched deep-sea water inhibits the metastatic potential of human breast cancer cell lines. Int J Oncol. 2013

Lee DH. Protective effects of deep sea water against doxorubicininduced cardiotoxicity in H9c2 cardiac muscle cells. Int J Oncol. 2014 Dec;45(6):2569-75.

Liu HY. Potential Osteoporosis Recovery by Deep Sea Water through Bone Regeneration in SAMP8 Mice. Evid Based Complement Alternat Med. 2013;2013:161976.

Maehira F, Iinuma Y, Eguchi Y, Miyagi I, Teruya S. Effects of soluble silicon compound and deep-sea water on biochemical and mechanical properties of bone and the related gene expression in mice. Journal of Bone and Mineral Metabolism. 2008;26(5):446–455.

Ha BG. Stimulatory Effects of Balanced Deep Sea Water on Mitochondrial Biogenesis and Function. PLoS One. 2015 Jun 12;10(6):e0129972.

Kawada M, Takeuchi H, Con SA, Yamamoto E, Yasukawa T, et al. (2012) Antibacterial Activities of Refined Deep Seawater on Helicobacter pylori. J Medical Microbiol Diagnosis S1:002.

Tsuchiya Y, Watanabe A, Fujisawa N, Kaneko T, Ishizu T, et al. (2004) Effects of desalted deep seawater on hematologic and blood chemical values in mice. Tohoku J Exp Med 203: 175-182.

Yang CC . Deep-sea water containing selenium provides intestinal protection against duodenal ulcers through the upregulation of Bcl-2 and thioredoxin reductase 1. PLoS One. 2014 Jul 1;9(7):e96006.

Katsuda S, Yasukawa T, Nakagawa K, Miyake M, Yamasaki M, et al. (2008) Deep-sea water improves cardiovascular hemodynamics in Kurosawa and Kusanagi-Hypercholesterolemic (KHC) rabbits. Biol Pharm Bull 31: 38-44.

WENG SI KOU et al. Deep-sea water administration efficiently inhibits the growth of Helicobacter pylori through the inhibition of caspase-1/inflammasome/pyroptosis signaling. April 2016. The FASEB Journal vol. 30 no. 1 Supplement 1253.2

Jyh-Chin Yang, M.D.Ph.D. Anti-H. Pylori Effect of Deep Sea Water. National Taiwan University Hospital

Chen IS et al. Alleviative effects of deep-seawater drinking water on hepatic lipid accumulation and oxidation induced by a high-fat diet. J Chin Med Assoc. 2013 Feb;76(2):95-101.

Ha BG et al. Effects of balanced deep-sea water on adipocyte hypertrophy and liver steatosis in high-fat, diet-induced obese mice. Obesity (Silver Spring). 2014 Jul;22(7):1669-78.

He S et al. Modulation of lipid metabolism by deep-sea water in cultured human liver (HepG2) cells. Mar Biotechnol (NY). 2014 Apr;16(2):219-29.

Hsu TC et al. Attenuated Effects of Deep-Sea Water on Hepatic Apoptosis in STZ-Induced Diabetic Rats. Chin J Physiol. 2015 Jun 30;58(3):197-205.

Eau de mer & Anti-âge

Necessità di un corretto equilibrio idroelettrolitico nell’anziano con demenza: Il Plasma Marino. Lacava R., Castagna A., Aversa A., Cotroneo A.M., Mazzei F., Pontieri M.T., Costantino D.S., Gareri P. 58° Congresso Nazionale sigg – Comunicazioni Orali e Poster

Lacava, Roberto & Castagna, Alberto & Mazzei, Francesca & Teresa Pontieri, Maria & Maria Cotroneo, Antonino & Aversa, Antonio & Gareri, Pietro. (2014). THE ROLE OF THE MARINE PLASMA IN THE ELDERLY WITH DEMENTIA AND HYPOVOLEMIA. Alzheimer’s & Dementia. 10. P490. 10.1016/j.jalz.2014.05.730.

Study of the potential geroprotector “Quinton Marine Plasma experiments” in cultured cells. Хохлов А.Н., Клебанов А.А., Рындина Т.С., Насонов М.М., Coll F.

On the influence of potential geroprotector “Quinton Marine Plasma “on the viability of cultured cells of Chinese. Рындина Т.С., Coll F., Хохлов А.Н.

Eau de mer, chaleur et sport


Sawka MN, Montain SJ. Fluid and electrolyte supplementation for exercise heat stress. Am J Clin Nutr. 2000 Aug;72(2 Suppl):564S-72S.

Chinevere TD et al. Effect of heat acclimation on sweat minerals. Med Sci Sports Exerc. 2008 May;40(5):886-91.

Equilibre acido-basique

Pizzorno J, Frassetto LA, Katzinger J. Diet-induced acidosis: is it real and clinically relevant? Br J Nutr. 2010 Apr;103(8):1185-94.

Bushinsky DA. Acid-base imbalance and the skeleton. Eur J Nutr. 2001 Oct;40(5):238-44

Tucker KL, Hannan MT, Kiel DP. The acid-base hypothesis: diet and bone in the Framingham Osteoporosis Study. Eur J Nutr. 2001 Oct;40(5):231-7.

Macdonald HM, New SA, et al. Low dietary potassium intakes and high dietary estimates of net endogenous acid production are associated with low bone mineral density in premenopausal women and increased markers of bone resorption in postmenopausal women. Am J Clin Nutr. 2005 Apr;81(4):923-33.

Ian F. Robey, Brenda K. Baggett, Nathaniel D. Kirkpatrick et al. Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases. Cancer Research 69, 2260, March 15, 2009

Regina Maria Cseuz, Istvan Barna, Tamas Bender, Jürgen Vormann. Alkaline Mineral Supplementation Decreases Pain in Rheumatoid Arthritis Patients: A Pilot Study. The Open Nutrition Journal, 2008, 2, 100-105

– Vormann J, Worlitschek M, Goedecke T, Silver B. Supplementation with alkaline minerals reduces symptoms in patients with chronic low back pain. J Trace Elem Med Biol 2001; 15: 179-83.


Actividad inmunomoduladora de la solución isotónica e hipertónica quinton Ex Vivo. Dr. José Miguel Sempere Ortells. Tokyo, 2010.

Actividad inmunomoduladora de la solución isotónica e hipertónica quinton en artritis reumatoide y en lupus. Dr. José Miguel Sempere Ortells. Alicante, 2010


Vérification et mesure comparative de la vitalité et de la mobilité des spermatozoïdes immergés dans différentes solutions d’eau de mer isotoniques. PROTOCOLE Dominique HOAREAU/Catherine WILLARD. Laboratoire de Biologie Médicale Tour d’Aigues. Décembre 2002.

Air marin et ions négatifs

Reilly T, Stevenson IC. An investigation of the effects of negative air ions on responses to submaximal exercise at different times of day.

Suzuki S. et al. Effects of negative air ions on activity of neural substrates involved in autonomic regulation in rats. Int J Biometeorol. 2008 Jul;52(6):481-9. doi: 10.1007/s00484-007-0143-2. Epub 2008 Jan 11.

Reilly T. et al. An investigation of the effects of negative air ions on responses to submaximal exercise at different times of day. J Hum Ergol (Tokyo). 1993 Jun;22(1):1-9.

L.H.Hawkins et al. The influence of air ions, temperature and humidity on subjective wellbeing and comfort. Journal of Environmental Psychology. Volume 1, Issue 4, December 1981, Pages 279-292

Jacob Gabbay et al. Effect of ionization on microbial air pollution in the dental clinic. Environmental Research. Volume 52, Issue 1, June 1990, Pages 99-106

Escombe AR et al. Upper-room ultraviolet light and negative air ionization to prevent tuberculosis transmission. PLoS Med. 2009 Mar 17;6(3):e43. doi: 10.1371/journal.pmed.1000043.

Eau de Mer & Peau

Denda M. Negative electric potential induces alteration of ion gradient and lamellar body secretion in the epidermis, and accelerates skin barrier recovery after barrier disruption. J Invest Dermatol. 2002 Jan;118(1):65-72.

Dubarry J et Tamarelle C: étude expérimentale de la pénétration de quelques éléments marqués à travers les téguments et leur distribution dans l’organisme (Revue Internationale d’océanographie médicale, tome XXI, 1973)

Beatriz Ortíz Ortíz, María Jesús Santandreu Capón. Use of sea water in milk diet babies eczema.

Sels Minéraux

Sarthou G., Bucciarelli E., Chever F., Hansard S. P., González-Dávila M., Santana-Casiano J. M., Planchon F., Speich S., 2011. Labile Fe(II) concentrations in the Atlantic sector of the Southern Ocean along a transect from the subtropical domain to the Weddell Sea Gyre. Biogeosciences, 8, 2461-2479.


Galan P. et al. Dietary magnesium intake in a French adult population. Magnes Res. 1997 Dec;10(4):321-8.

Marian Semczuk, Anna Semczuk-Sikora. New data on toxic metal intoxication (Cd, Pb, and Hg in particular) and Mg status during pregnancy. Med Sci Monit 2001; 7(2): RA332-340

Wark PA et al. Magnesium intake and colorectal tumor risk: a case-control study and meta-analysis. Am J Clin Nutr. 2012 Sep;96(3):622-31. doi: 10.3945/ajcn.111.030924. Epub 2012 Aug 1.

Wark PA, Lau R, Norat T and Kampman E: Magnesium intake and colorectal tumor risk: a case-control study and meta-analysis. Am J Clin Nutr. 96:622–631. 2012.

Izuoka T, Toyama M, Higuchi T, Kobayashi K, Mitsui H, et al. (2009) Postmarketing functional food survey: efficacy and safety of magnesium-containing mineral water for patients with constipation. Journal of Japan Physicians Association (JJPA) 24: 102-107.

Sun Ha Jee et al. The effect of magnesium supplementation on blood pressure: a meta-analysis of randomized clinical trials. Am J Hypertens (2002) 15 (8): 691-696.

Dupont C et al. Efficacy and safety of a magnesium sulfate-rich natural mineral water for patients with functional constipation. Clin Gastroenterol Hepatol. 2014 Aug;12(8):1280-7

Sel & Santé

Hiroyuki Takase et al. Dietary Sodium Consumption Predicts Future Blood Pressure and Incident Hypertension in the Japanese Normotensive General Population. J Am Heart Assoc. 2015 Aug; 4(8): e001959. Published online 2015 Jul 29. doi: 10.1161/JAHA.115.001959

Murai S. et al. LITTLE DIFFERENCE IN SALT INTAKE CRUCIALLY AFFECTS FUTURE BLOOD PRESSURE LEVELS IN THE GENERAL POPULATION. J Hypertens. 2015 Jun;33 Suppl 1:e68. doi: 10.1097/01.hjh.0000467531.97498.3a.

Mente A et al. PURE Investigators. Association of urinary sodium and potassium excretion with blood pressure. N Engl J Med. 2014;371:601–611.

Mente et coll. Urinary sodium and potassium excretion, mortality, and cardiovascular events. NEJM, août 2014. doi: 10.1056/NEJMoa1311889 371:612-23

Mozaffarian et coll. Global sodium consumption and death from cardiovascular causes. NEJM, août 2014. doi: 10.1056/NEJMoa1304127

Chang HY et al. Effect of potassium-enriched salt on cardiovascular mortality and medical expenses of elderly men. Am J Clin Nutr. 2006 Jun;83(6):1289-96.

The effects of nonpharmacologic interventions on blood pressure of persons with high normal levels. Results of the Trials of Hypertension Prevention, Phase I. JAMA. 1992;267:1213–1220.

He FJ, MacGregor GA. Effect of modest salt reduction on blood pressure: a meta-analysis of randomized trials. Implications for public health. J Hum Hypertens. 2002;16:761–770.

Adam Drewnowski et al. The feasibility of meeting the WHO guidelines for sodium and potassium: a cross-national comparison study. BMJ Open 2015;5:e006625 doi:10.1136/bmjopen-2014-006625

Linda A. J. van Mierlo et al. Suboptimal Potassium Intake and Potential Impact on Population Blood Pressure. Archives of Internal Medicine, 2010; 170 (16): 1501-1502 DOI: 10.1001/archinternmed.2010.284

Souza Bda S. et al. Soft drink consumption, mainly diet ones, is associated with increased blood pressure in adolescents. J Hypertens. 2016 Feb;34(2):221-5. doi: 10.1097/HJH.0000000000000800.

Perez-Pozo SE et al. Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response. Int J Obes (Lond). 2010 Mar;34(3):454-61. doi: 10.1038/ijo.2009.259. Epub 2009 Dec 22.

Kodama N, et al. Negative balance of calcium and magnesium under relatively low sodium intake in humans. Randomized controlled trial. J Nutr Sci Vitaminol (Tokyo). 2003 Jun;49(3):201-9.

Nishimuta M, et al.  Positive correlation between dietary intake of sodium and balances of calcium and magnesium in young Japanese adults–low sodium intake is a risk factor for loss of calcium and magnesium— J Nutr Sci Vitaminol (Tokyo). 2005.


Forestier R, Desfour H, Tessier JM, Françon A, Foote A, Genty C, Rolland C, Roques CF, Bosson J. Spa therapy in the treatment of knee osteoarthritis, a large randomised multicentre trial. Ann Rheum Dis published online 3 Sep 2009.

Kjellgren A. et al. Beneficial effects of treatment with sensory isolation in flotation-tank as a preventive health-care intervention – a randomized controlled pilot trial. BMC Complement Altern Med. 2014 Oct 25;14:417.

Proksch E, Nissen HP, Bremgartner M, Urquhart C (2005) Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin. Int J Dermatol

Young AJ, Muza SR, Sawka MN, Pandolf KB. Human vascular fluid responses to cold stress are not altered by cold acclimation. Undersea Biomed Res. 1987 May;14(3):215-28.

Proksch, Ehrhardt MD, PhD et al. Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin. International Journal of Dermatology, February 2005. Retrieved on 2008-04-13.

Ehrhardt, Proksch; Nissen, HP; Bremgartner, M; Urquhart, C. Bathing in a magnesium-rich Dead Sea salt solution: follow-on review. International Journal of Dermatology 46 (2): 177–179.

Adler-Cohen C, Czarnowicki T, Dreiher J, Ruzicka T, Ingber A, Harari M. Climatotherapy at the Dead Sea: an effective treatment modality for atopic dermatitis with significant positive impact on quality of life. Dermatitis. 2012 Mar-Apr;23(2):75-80.

Sukenik S, Flusser D, Codish S, Abu-Shakra M. Balneotherapy at the Dead Sea area for knee osteoarthritis. Isr Med Assoc J. 1999 Oct;1(2):83-5.

Alimentation Bio

Lu C., Toepel K., Irish R., Fenske R.A., Barr D.B., Bravo R. (2006). Organic diets significantly lower children’s dietary exposure to organophosphorus pesticides. Environ Health Perspect 114:260-263.

Oates, L., Cohen M., Schembri A., Taskova R. (2014). Reduction in urinary organophosphate pesticide metabolites in adults after a week-long organic diet. Environmental Research, 132 pp 105-111


Lulu Xie et al. Sleep Drives Metabolite Clearance from the Adult Brain. Science 18 October 2013. Vol. 342 no. 6156 pp. 373-377

Benedict C. et al. Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men. Sleep. 2014 Jan 1;37(1):195-8.

Spaeth AM; Dinges DF; Goel N. Effects of experimental sleep restriction on weight gain, caloric intake, and meal timing in healthy adults. SLEEP 2013;36(7):981-990.

Michael D. Drennan et al. Potassium Affects Actigraph-Identified Sleep. Sleep (1991) 14 (4): 357-360.

Exposition solaire & Vitamine D

Cui Y and Rohan TE: Vitamin D, calcium, and breast cancer risk: a review. Cancer Epidemiol Biomarkers Prev. 15:1427–1437. 2006.

Lappe JM, Travers-Gustafson D, Davies KM, Recker RR and Heaney RP: Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr. 85:1586–1591. 2007.

Intoxication des populations

Stéphanie Vandentorren, Laurence Guldner. Dosage des biomarqueurs en maternité dans le cadre de l’enquête pilote Elfe (Étude longitudinale française depuis l’enfance), octobre 2007. Institut de Veille Sanitaire.

Institut de Veille Sanitaire. Exposition de la population française aux polluants de l’environnement. Volet environnemental de l’étude nationale nutrition santé.

Centers for Disease Control and Prevention (CDC). Fourth National Report on Human Exposure to Environmental Chemicals, 2009. Updated Tables, February 2015.

Santé Canada. Rapport sur la biosurveillance humaine des substances chimiques de l’environnement au Canada.

F. Péhourcq , M. Molimard. Pharmacocinétique chez le sujet âgé. Revue des Maladies Respiratoires Vol 21, N° 5-c3  – novembre 2004 pp. 825

Expositions aux agents chimiques cancérogènes : des mesures de protection encore insuffisantes. Revue Prescrire. Janvier 2017. Tome 37 n°399. Pages 66-67.

M. Rolland et al. Decline in semen concentration and morphology in a sample of 26 609 men close to general population between 1989 and 2005 in France. Hum. Reprod. (2012) doi: 10.1093/humrep/des41

Carlsen E. et al. Evidence for decreasing quality of semen during past 50 years. BMJ. 1992 Sep 12;305(6854):609-13.

J. Le Moal, S. Goria, V. Wagner, P. de Crouy-Chanel, A. Rigou, J. De Mouzon. Tendances temporelles régionales de la qualité du sperme et hypothèses environnementales. Revue d’Épidémiologie et de Santé Publique, Volume 62, Issue null, Page S208

Jonathan G. Boucher  et al. In Vitro Effects of Bisphenol A β-D-Glucuronide (BPA-G) on Adipogenesis in Human and Murine Preadipocytes. Environ Health Perspect; DOI:10.1289/ehp.1409143


Commissariat Général au Développement Durable. Les pesticides dans les cours d’eau français en 2013. Chiffres et statistiques. Novembre 2015.

Jörgen Magnér, Petra Wallberg, Jasmin Sandberg, Anna Palm Cousins. Human exposure to pesticides from food. A pilot study. For Coop Sverige AB

Cynthia L Curl, Richard A Fenske, and Kai Elgethun. Organophosphorus pesticide exposure of urban and suburban preschool children with organic and conventional diets. Environ Health Perspect. 2003 Mar; 111(3): 377–382.

Institut de Recherche Environnementale Suédois IVL Swedish Environmental Research Institute. Human Exposure to Pesticides From Food.

Pesticides à usage domestique et leucémies aiguës chez les enfants. Revue Prescrire. Juillet 2017. Tome 37 n°405. Pages 539-540.


Alexandra ter Halle, Lucie Ladirat, Xavier Gendre, Dominique Goudouneche, Claire Pusineri, Corinne Routaboul, Christophe Tenailleau, Benjamin Duployer, Emile Perez. Understanding the Fragmentation Pattern of Marine Plastic Debris. Environ Sci Technol. 2016 May 23.

Andrés Cózar et al. Plastic debris in the open ocean. Proceedings of the National Academy of Science vol. 111 no. 28, 10239–10244, doi: 10.1073/pnas.1314705111

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Anne F.C. Leonard, Lihong Zhang, Andrew J. Balfour, Ruth Garside, Peter M. Hawkey, Aimee K. Murray, Obioha C. Ukoumunne, William H. Gaze. Exposure to and colonisation by antibiotic-resistant E. coli in UK coastal water users: Environmental surveillance, exposure assessment, and epidemiological study (Beach Bum Survey). Environment International. Available online 14 January 2018

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UFC – Que Choisir. Substances préoccupantes dans 185 produits cosmétiques. Les consommateurs appelés à passer à l’action ! Publié en ligne le 22/02/2016

Sa Liu et al. Concentrations and Potential Health Risks of Metals in Lip Products. Environ Health Perspect; DOI:10.1289/ehp.1205518

Mandriota SJ. A Case-control Study Adds a New Piece to the Aluminium/Breast Cancer Puzzle. EBioMedicine. 2017 Aug;22: 22-23. doi: 10.1016/j.ebiom.2017.06.025. Epub 2017 Jun 27.

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Crèmes solaires

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David Sánchez-Quiles and Antonio Tovar-Sánchez. Sunscreens as a Source of Hydrogen Peroxide Production in Coastal Waters. Environ. Sci. Technol., 2014, 48 (16), pp 9037–9042

Anders Goksøyr et al. Balsa Raft Crossing the Pacific Finds Low Contaminant Levels. Article in Environmental Science and Technology 43(13):4783-90 · August 2009.

Morgane Bachelot et al. Organic UV filter concentrations in marine mussels from French coastal regions. Science of The Total Environment 420:273-9

Roberto Danovaro et al. Sunscreens Cause Coral Bleaching by Promoting Viral Infections. Environ Health Perspect. 2008 Apr; 116(4): 441–447.

C. A. Downs et al. Toxicopathological Effects of the Sunscreen UV Filter, Oxybenzone (Benzophenone-3), on Coral Planulae and Cultured Primary Cells and Its Environmental Contamination in Hawaii and the U.S. Virgin Islands. Archives of Environmental Contamination and Toxicology. February 2016, Volume 70, Issue 2, pp 265–288

Maipas S. et al. Sun lotion chemicals as endocrine disruptors. Hormones (Athens). 2015 Jan-Mar;14(1):32-46.

Perturbations de l’Océan

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David J. R. Thornalley et al. Anomalously weak Labrador Sea convection and Atlantic overturning during the past 150 years. Nature, 2018; 556 (7700): 227 DOI: 10.1038/s41586-018-0007-4

Caesar et al. Observed fingerprint of a weakening Atlantic Ocean overturning circulation. Nature, 2018; 556 (7700): 191 DOI: 10.1038/s41586-018-0006-5


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